tldr; No sane drug professionals would have designed a relatively simple compound (144 Atomic Mass) as a Multiple Sclerosis drug
I think human review may screw things up. If you look at dimethyl fumarate[1], no card carrying medicinal chemist would have taken this serious. No pharma exec would have risked 100s of millions of dollars for clinical research trials.
- 1950s people notices that a wood polish cleared psoriasis. Topical formulation worked.
- 1990s an oral formulation was created.
- 2000s people noticed people treated for psoriasis that had MS, had fewer MS symptoms while taking this molecule.
- 2017 dimethyl fumerate is approved for MS.
[1] https://en.wikipedia.org/wiki/Dimethyl_fumarate
>The precise mechanism of action of dimethyl fumarate is not clear.
And here is the real problem. Instead of burning gigawatthours of power with GPUs, if Anthropic really wanted to help bioscience, they should just be throwing their $2 trillion at making it possible to live off of studying things like this.
We aren't in a place where a magic "Intelligence" could just look at the data and solve all our problems because we have never funded the collection of that data in the first place
We spent a lot of money on the Human Genome project and got large dividends from it but seemingly never reinvested! There's so many clear and straightforward questions we should be answering in biology that we just aren't, because nobody wants to pay for it.
I think human review may screw things up. If you look at dimethyl fumarate[1], no card carrying medicinal chemist would have taken this serious. No pharma exec would have risked 100s of millions of dollars for clinical research trials.