To some degree, yes. Not to the point that I can't or won't do it, but I would certainly prefer books to be printed much wider. I can mitigate some of the issue by keeping my index finger along the left margin as I read, so I have a better idea of where my eyes need to jump to the next line. That technique is impossible with my computer screen, which is more than arm's length from me.

Part of the issue is that I read fairly quickly, so I find myself spending a relatively large percentage of my time skipping to the next line, and it's that frequent context switching that is annoying.